Over-the-counter statins.
نویسندگان
چکیده
In late 2004, the British government decided to allow a lipid-lowering agent to be sold as an over-the-counter medication. In contrast, the U.S. Food and Drug Administration recently decided not to do so. The United States and other countries will soon face similar decisions for other statins. Although statins have infrequent side effects and have been shown to be effective in moderate-risk primary prevention populations, many questions remain unanswered about their effectiveness at lower doses in over-the-counter use, the ability of patients to self-select themselves for appropriate therapy, and the social and economic implications associated with this method of distribution for preventive medications. A rational policy decision concerning over-the-counter statin use will require an effectiveness trial to provide data on how such drugs would be used in this context, as well as on the clinical outcomes that could be expected from this novel "route of administration."
منابع مشابه
Impact of a policy allowing for over-the-counter statins.
BACKGROUND allowing statins to be sold without a prescription has been widely debated in Great Britain, Canada and the USA. AIMS To examine the impact of the recent policy in Great Britain allowing patients to purchase over-the-counter (OTC) 10 mg dose of a cholesterol-lowering drug (simvastatin) on meeting the needs of individuals at moderate risk of coronary heart disease (CHD). METHODS w...
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ورودعنوان ژورنال:
- Annals of internal medicine
دوره 142 11 شماره
صفحات -
تاریخ انتشار 2005